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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRY1
All Species:
36.06
Human Site:
S194
Identified Species:
61.03
UniProt:
Q16526
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16526
NP_004066.1
586
66395
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Chimpanzee
Pan troglodytes
XP_509339
586
66344
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Rhesus Macaque
Macaca mulatta
XP_001100653
586
66450
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Dog
Lupus familis
XP_531757
606
68237
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Cat
Felis silvestris
Mouse
Mus musculus
P97784
606
67983
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Rat
Rattus norvegicus
Q32Q86
588
66212
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508613
577
65001
S155
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Chicken
Gallus gallus
Q8QG61
621
69654
S194
D
E
K
Y
G
V
P
S
L
E
E
L
G
F
D
Frog
Xenopus laevis
Q75WS4
523
60626
E168
T
Q
F
R
K
A
V
E
T
Q
G
K
V
R
P
Zebra Danio
Brachydanio rerio
Q4KML2
520
59903
A165
V
Y
T
Q
F
R
K
A
V
E
A
Q
G
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77059
542
62494
Q159
G
I
P
P
L
T
Y
Q
M
F
L
H
T
V
Q
Honey Bee
Apis mellifera
NP_001077099
570
65246
T212
D
D
H
Y
G
V
P
T
L
E
E
L
G
F
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785873
516
59965
N159
E
I
L
A
L
N
N
N
E
P
P
L
T
Y
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96524
612
69439
E195
S
I
E
E
L
G
L
E
N
E
A
E
K
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.4
95.3
N.A.
93.5
96.2
N.A.
85.3
87.5
25.7
25
N.A.
37.2
65.3
N.A.
59.5
Protein Similarity:
100
100
99.6
95.8
N.A.
94.7
97.7
N.A.
89.2
92.1
43.5
42.3
N.A.
53.7
78.5
N.A.
70.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
13.3
N.A.
0
80
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
13.3
26.6
N.A.
6.6
93.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
0
0
15
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
8
0
0
0
0
0
0
0
0
0
0
0
0
65
% D
% Glu:
8
58
8
8
0
0
0
15
8
79
65
8
0
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
8
0
0
0
65
0
% F
% Gly:
8
0
0
0
65
8
0
0
0
0
8
0
72
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
22
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
58
0
8
0
8
0
0
0
0
8
8
0
8
% K
% Leu:
0
0
8
0
22
0
8
0
65
0
8
72
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
65
0
0
8
8
0
0
8
8
% P
% Gln:
0
8
0
8
0
0
0
8
0
8
0
8
0
0
8
% Q
% Arg:
0
0
0
8
0
8
0
0
0
0
0
0
0
15
0
% R
% Ser:
8
0
0
0
0
0
0
58
0
0
0
0
0
0
8
% S
% Thr:
8
0
8
0
0
8
0
8
8
0
0
0
15
0
0
% T
% Val:
8
0
0
0
0
65
8
0
8
0
0
0
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
65
0
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _